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Journal of Oncology Pharmacy Practice
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1078155208094454v1
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Article

Propofol extravasation in a breast cancer patient

E.J.M. Huijbers1*, J.W. Baars2, P.F.E. Schutte3, J.H.M. Schellens2, and Jos Beijnen4

1 Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute/Slotervaart Hospital, Louwesweg 6, 1066 EC Amsterdam, The Netherlands
2 Department of Medical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
3 Department of Anaesthesiology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
4 Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute/Slotervaart Hospital, Louwesweg 6, 1066 EC Amsterdam, The Netherlands; Department of Medical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

* To whom correspondence should be addressed.


  Abstract

A breast cancer patient experienced an accidental propofol extravasation in the dorsum of her hand during a Port-A-Cath replacement. She had heavy pain which was treated with analgesics. The patient's hand was cooled and kept in an upright position. Three days later the patient received her last AC (adriamycin/cyclophosphamide) course without complications. Propofol extravasation did not result in tissue necrosis in this case. AC chemotherapy could be administered safely 3 days after propofol extravasation.

Key Words: propofol, extravasation, anaesthesia, accidental, treatment (propofol010508)

First published on August 27, 2008, doi:10.1177/1078155208094454

Journal of Oncology Pharmacy Practice 2008;14:195.

A more recent version of this article appeared on December 1, 2008

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