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Priorities and uncertainties of administering chemotherapy in a pregnant woman with newly diagnosed colorectal cancer

Mary Babb Randolph Cancer Center, Section of Hematology/ Oncology, Department of Medicine, West Virginia University, Morgantown, WV 26506, USA

Miklos L Auber, MD

Mary Babb Randolph Cancer Center, Section of Hematology/ Oncology, Department of Medicine, West Virginia University, Morgantown, WV 26506, USA

Gerald M Higa, PharmD

Mary Babb Randolph Cancer Center, Section of Hematology/ Oncology, Department of Medicine, West Virginia University, Morgantown, WV 26506, USA, ghiga{at}hsc.wvu.edu

Background. The absence of treatment standards for the use of chemotherapy in pregnancy is due, in part, to the fact that cancer in the gravid female is relatively uncommon.

Method. A case (of a pregnant woman with newly diagnosed colorectal cancer) is presented to explore this area of medical uncertainty.

Result. Managed by a multi-disciplinary team, successful prolongation of gestation was achieved with an oxaliplatin-based chemotherapy regimen.

Conclusion. A perspective of the ongoing conflict between prolonging the mother's life and preserving fetal development is highlighted. Although not life-saving, administration of chemotherapy in this woman was life-sparing. J Oncol Pharm Practice (2009) 15: 5—8.

Key Words: abortion • cancer in pregnancy • chemotherapy • colorectal cancer

This version was published on March 1, 2009

Journal of Oncology Pharmacy Practice, Vol. 15, No. 1, 5-8 (2009)
DOI: 10.1177/1078155208094101


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