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Journal of Oncology Pharmacy Practice
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*Compound via MeSH
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*Breast Cancer
Hazardous Substances DB
*CYCLOPHOSPHAMIDE
*DOXORUBICIN
*PROPOFOL
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Propofol extravasation in a breast cancer patient

EJM Huijbers

Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute/Slotervaart Hospital, Louwesweg 6, 1066 EC Amsterdam, The Netherlands

JW Baars

Department of Medical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

PFE Schutte

Department of Anaesthesiology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

JHM Schellens

Department of Medical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

JH Beijnen

Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute/Slotervaart Hospital, Louwesweg 6, 1066 EC Amsterdam, The Netherlands, j.beijnen{at}nki.nl or apjby{at}slz.nl, Department of Medical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

A breast cancer patient experienced an accidental propofol extravasation in the dorsum of her hand during a Port-A-Cath replacement. She had heavy pain which was treated with analgesics. The patient's hand was cooled and kept in an upright position. Three days later the patient received her last AC (adriamycin/ cyclophosphamide) course without complications. Propofol extravasation did not result in tissue necrosis in this case. AC chemotherapy could be administered safely 3 days after propofol extravasation.

Key Words: propofol • extravasation • anaesthesia • accidental • treatment (propofol010508)

This version was published on December 1, 2008

Journal of Oncology Pharmacy Practice, Vol. 14, No. 4, 195-198 (2008)
DOI: 10.1177/1078155208094454
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