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Oncology medication safety: A 3D status report 2008

Moffitt Cancer Center, Tampa, FL, phil.johnson{at}moffitt.org

Carole R Chambers, BSc (Pharm) MBA

Alberta Cancer Board, Alberta Canada

Allen J Vaida, PharmD FASHP

Institute for Safe Medication Practices, Horsham, PA

Background. The safe use of medications is a major concern in oncology practice. Three organizations collaborated on a survey to determine if practitioners had implemented current recommended safe practices for IV vincristine administration, general oncology safe practices, and safe practices for oral chemotherapy.

Methods. A survey was distributed to members of the Hematology Oncology Pharmacy Association (HOPA) and the International Society of Pharmacy Practitioners (ISOPP) using Survey Monkey ^TM. The Institute of Safe Medication Practices (ISMP) also solicited readers of its Medication Safety Alert! ^® to respond to the survey. A comparison to results from a survey conducted by ISMP in 2006 on safe practices for IV vincristine was also conducted.

Results. The majority of respondents were aware of the WHO recommendations for IV vincristine, although the rate of implementation of the guidelines ranged from 24.1 to 53.6%. When compared to the ISMP 2006 survey there was a 25.8—37.4% improvement in following many of the safe practice guidelines. Administering IV vincristine via a minibag showed the lowest rate of adoption (less than 40%). Of the 35 survey items on general chemotherapy safety strategies, 80% of respondents had implemented at least 21 items in the survey. Overall 32.4% of respondents did not consider oral chemotherapy as requiring the same safety concerns as parenteral therapy.

Conclusions. The results of this survey will provide a new baseline for the adoption rate of safe medication practice recommendations related to oncology. Further work on addressing barriers in adopting identified safe practice recommendations needs to be conducted.

Key Words: medication safety • oncology • error prevention

This version was published on December 1, 2008

Journal of Oncology Pharmacy Practice, Vol. 14, No. 4, 169-180 (2008)
DOI: 10.1177/1078155208097634


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