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Journal of Oncology Pharmacy Practice
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Actinic keratosis and capecitabine therapy

Gerald M Higa, PharmD

Department of Medicine, Section of Hematology/Oncology, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV, USA

Rodney F Kovach, MD

Department of Medicine, Section of Dermatology

Jame Abraham, MD

Department of Medicine, Section of Hematology/Oncology, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV, USA

Topical application of 5-fluorouracil (5-FU) is one of the most effective clinical strategies available to treat actinic keratosis (AK). During treatment, an apparent toxic skin reaction occurs before dermal quiescence ensues. We report a case of a typical flare of AK in a woman treated with capecitabine for advanced breast cancer.

Key Words: actinic keratosis • capecitabine • 5-FU

Journal of Oncology Pharmacy Practice, Vol. 11, No. 4, 151-153 (2005)
DOI: 10.1191/1078155205jp163cr


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