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An evaluation of six infusion devices for the continuous infusion of cytotoxic drugs in ambulatory patients

Medicines Research Unit, Department of Pharmacy, Royal Devon & Exeter Hospital, Exeter, United Kingdom

C. Williamson, BPharm

Medicines Research Unit, Department of Pharmacy, Royal Devon & Exeter Hospital, Exeter, United Kingdom

G.J. Sewell, PhD

Medicines Research Unit, Department of Pharmacy, Royal Devon & Exeter Hospital, Exeter, United Kingdom

Introduction. The clinical, economic, and user attributes of six ambulatory infusion devices were evaluated for their inclusion into the Home Oncol ogy Program, Exeter (HOPE).

Methods. Devices evaluated included; Graseby MS-26 syringe driver, Graseby 9100, Pharmacia CADD-1, Parker-Strato 2100 micropump (now un available), Baxter Multiday Infusor, and Infu-med 300. Criteria evaluated included accuracy, preci sion, in-use observations, capital cost, consumable cost, estimated monthly cost, degree of patient intervention, and patient comfort. A quality of life evaluation was undertaken in a more detailed assessment on the Graseby MS-26 and Infu-Med 300 device used routinely in the HOPE pro gramme.

Results. On the basis of these studies, the Parker-Strato 2100 pump was the preferred device although this has subsequently been withdrawn from the market. However, the newly developed Graseby 9000 series device was found to possess many of the qualities of the Parker-Strato pump and has been selected for further trials in this institu tion.

Key Words: Ambulatory • pump • infusion device • chemotherapy.

Journal of Oncology Pharmacy Practice, Vol. 1, No. 1, 15-22 (1995)
DOI: 10.1177/107815529500100102


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